Fetal tendon wound size modulates wound gene expression and subsequent wound phenotype
نویسندگان
چکیده
منابع مشابه
Wound pH depends on actual wound size
Wound healing is an intricate process that involves many types of cells, reaction pathways as well as chemical, physical and electrical cues. Since biochemical reactions and physiological events are pH-dependent we study here pH as an important major characteristic of the wound healing process in the presence of endogenous and exogenous electric fields. Our model gives the spatial pH distributi...
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Topical application of dexpanthenol is widely used in clinical practice for the improvement of wound healing. Previous in vitro experiments identified a stimulatory effect of pantothenate on migration, proliferation and gene regulation in cultured human dermal fibroblasts. To correlate these in vitro findings with the more complex in vivo situation of wound healing, a clinical trial was perform...
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Fetal skin has the intrinsic capacity for wound healing, which is not correlated with the intrauterine environment. This intrinsic ability requires biochemical signals, which start at the cellular level and lead to secretion of transforming factors and expression of receptors, and specific markers that promote wound healing without scar formation. The mechanisms and molecular pathways of wound ...
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OBJECTIVE The goal of this study was to evaluate whether simple risk factors can be identified that successfully characterize who will heal and who will not heal among patients who have received standard therapy for diabetic neuropathic foot ulcers. RESEARCH DESIGN AND METHODS For this cohort study, we evaluated >31,000 individuals with a diabetic neuropathic foot ulcer seen in the Curative H...
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ژورنال
عنوان ژورنال: Wound Repair and Regeneration
سال: 2010
ISSN: 1067-1927
DOI: 10.1111/j.1524-475x.2010.00615.x